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Here, seizures were induced via intra-amygdala injection of kainic acid followed by administration of the AAV9-based CRISPRa therapy into the right ventral hippocampus to enhance KCNA1 expression (Colasante et al., 2020a)

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1,4 Early symptoms often include painful sensations, such as burning pain, electric shock-like sensations, sharp pains, and hyperalgesia